Phytochemical and Biological Effects of Sesamum  indicum L.- A Review

Khaled Rashed

doi:10.32439/ps.v5i1.8-11

Authors

Khaled Rashed

DOI:

https://doi.org/10.32439/ps.v5i1.8-11

Keywords:

Sesamum indicum L., Chemical compounds, Bioactivities

Abstract

Sesamum indicum L. is from Family Pedaliaceae. It plays an important role in ancient culture and modern system of medicine. It is commonly known as sesame. It is cultivated throughout India, mainly for its seeds and oil. The plant traditionally used in the treatment of hemorrhoids, dysentery, constipation, cough, amenorrhea, dysmenorrhea and ulcers. It also has antifungal, anticancer, antitumor, antiatherosclerotic activity. The total alcoholic extracts of all residual aerial parts of this plant show antioxidant, anticancer, antiaging and anticoagulant activities.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

H. A. Abou-Gharbia, A. A. Y. Shehata, and F. Shahidi, “Effect of processing on oxidative stability and lipid classes of sesame oil,” Food Research International, vol. 33, no. 5, pp. 331–340, 2000. DOI: https://doi.org/10.1016/S0963-9969(00)00052-1

M. Namiki, “Nutraceutical functions of sesame: a review,”Critical Reviews in Food Science and Nutrition,vol.47,no.7,pp.651–673, 2007. DOI: https://doi.org/10.1080/10408390600919114

M. Elleuch, S. Besbes, O. Roiseux, C. Blecker, and H. Attia, “Quality characteristics of sesame seeds and by-products,” Food Chemistry,vol.103,no.2,pp.641–650,2007. DOI: https://doi.org/10.1016/j.foodchem.2006.09.008

F. Shahidi, C.M. Liyana-Pathirana, and D. S. Wall, “Antioxidant activity of white and black sesame seeds and their hull fractions,” Food Chemistry, vol. 99, no.3, pp.478–483,2006. DOI: https://doi.org/10.1016/j.foodchem.2005.08.009

H. Zhang, H. Miao, L. Wei, C.Li, R. Zhao, and C. Wang, “Genetic analysis and Q T L mapping of seed coat color in sesame (Sesamum indicum L.),” PLoS ONE,vol.8,no.5, ArticleID e63898, 2013. DOI: https://doi.org/10.1371/journal.pone.0063898

Y. Zuo, C. Peng, Y. Liang et al., “Sesamin extends the meanlifespan of fruit lies,” Biogerontology, vol. 14, no.2, pp. 107–119, 2013. DOI: https://doi.org/10.1007/s10522-012-9413-4

M. Tada, Y. Ono, M. Nakai et al., “Evaluation of antioxidativeefects of sesamin on the in vivo hepatic reducing abilities by aradiofrequency ESR method,” Analytical Sciences, vol.29, no.1,pp.89–94,2013. DOI: https://doi.org/10.2116/analsci.29.89

M. Srisayam, N. Weerapreeyakul, S. Barusrux, and K. Kanokmedhakul, “Antioxidant, antimelanogenic, and skin-protective efect of sesamol,” Journal of Cosmetic Science,vol.65,no.2,pp.69–79,2014.

T. Furumoto and K. Nishimoto, “Identiication of a characteristic antioxidant, anthrasesamone F, in black sesame seeds and its accumulation at diferent seed developmental stages,”Bioscience, Biotechnology and Biochemistry,vol.80,no.2,pp. 350–355, 2016. DOI: https://doi.org/10.1080/09168451.2015.1091717

D.-Z. Hsu, C.-T. Liu, P.-Y. Chu, Y.-H. Li, S. Periasamy, and M.-Y. Liu, “Sesame oil attenuates ovalbumin-induced pulmonaryedema and bronchial neutrophilic inflammation in mice,” BioMed Research International, vol. 2013, Article ID 905670, 7, pages, 2013. DOI: https://doi.org/10.1155/2013/905670

P. Xu, F. Cai, X. Liu, and L. Guo, “Sesamin inhibits lipopo-lysaccharide-induced proliferation and invasion through thep38-MAPK and NF-B signaling pathways in prostate cancercells,” Oncology Reports,vol.33,no.6,pp.3117–3123,2015. DOI: https://doi.org/10.3892/or.2015.3888

A. A. Dar and N. Arumugam, “Lignans of sesame: puriication methods, biological activities and biosynthesis—a review,” Bioorganic Chemistry, vol.50, pp.1–10,2013. DOI: https://doi.org/10.1016/j.bioorg.2013.06.009

N.K. Jha, A.K. Jha; Phytopharm., 3-11 (2004).

C. Smith; Albert; Flora Vitiensis nova: a new flora of Fiji. National Tropical Botanical Garden, Lawai, Kauai, Hawaii. 5, 626 (1991).

C. Stone, Benjamin; The flora of Guam. Micronesica., 6, 1-659 (1970).

G.S. Chakraborthy, G. Sharma, K.N. Kaushik; Journal Herbal Medicine Toxicology, 2(2), 15-19 (2008).

F.Toshio, M.Iwata, A.F.M.Feroj, H.Fukui; Photochemistry, 64(4), 863-866 (2003). DOI: https://doi.org/10.1016/j.phytochem.2003.09.004

A.A. Moazzami, R.E. Andersson, A. Kamal-Eldin; Biotech. Biochem., 70(6), 1478-1481 (2006). DOI: https://doi.org/10.1271/bbb.60013

Ide T, Kushiro M, Takahashi Y, Shinohara K, Fukuda N, Yasumoto S. Sesamin, a sesame lignan, as a potent serum lipid-lowering food component. JARQ 2003;37(3):151-8. DOI: https://doi.org/10.6090/jarq.37.151

Wang BS, Chang LW, Yen WJ, Duh PD. Antioxidative effect of sesame coat on LDL oxidation and oxidative stress in macrophages. Food Chem 2007;102:351-60. DOI: https://doi.org/10.1016/j.foodchem.2006.05.026

Anand DT, Pothiraj C, Gopinath RM, Kayalvizhi B. Effect of oil-pulling on dental caries causing bacteria. Af J Mic Res 2008;2:063-6.

Nakano D, Kwak CJ, Fujii K, Ikemura K, Satake A, Ohkita M, et al. Sesamin metabolites induce an endothelial nitric oxide-dependent vasorelaxation through their antioxidative property-independent mechanisms: Possible involvement of the metabolites in the antihypertensive effect of sesamin. J Pharmacol Exp Ther 2006;318:328-35. DOI: https://doi.org/10.1124/jpet.105.100149

Nakano D, Itoh C, Takaoka M, Kiso Y, Tanaka T, Matsumura Y. Antihypertensive effect of sesamin. IV. Inhibition of vascular superoxide production by sesamin. Biol Pharm Bull 2002;25:1247-9. DOI: https://doi.org/10.1248/bpb.25.1247

Smith DE, Salerno JW. Selective growth inhibition of a human malignant melanoma cell line by sesame oil in vitro. Prostaglandins Leukot Essent Fatty Acids 1992;46(2):145-50. DOI: https://doi.org/10.1016/0952-3278(92)90221-4

Morton JF. Mucilaginous plants and their uses in medicine. J Ethnopharmacol 1990;29:245-66. DOI: https://doi.org/10.1016/0378-8741(90)90036-S